Characterization of Regulatory and Transporter Genes in the Biosynthesis of Anti-Tuberculosis Ilamycins and Production in a Heterologous Host
Ilamycins are cyclopeptides with novel structures that have been isolated from different Actinomycetes.They showed strong anti-tuberculosis activity and could serve as important anti-tuberculosis drug leads.The functions of the pre-tailoring and the post-tailoring genes in the biosynthesis of ilamycins have been elucidated, but the functions of the